Palladium-catalyzed intramolecular aerobic alkenylhydroxylation of allenamides with alkenyl iodides

Author:

Li Jun1234ORCID,Meng Long1234,Du Xin1234,Liu Qing1234,Xu Liping1234ORCID,Zhang Lizhi1234,Sun Fenggang1234ORCID,Li Xinjin1234ORCID,Zhang Daopeng1234,Xiao Xiao5674,Liu Hui1234ORCID

Affiliation:

1. School of Chemistry & Chemical Engineering

2. Shandong University of Technology

3. Zibo 255049

4. P. R. China

5. Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals

6. Zhejiang University of Technology

7. Hangzhou 310014

Abstract

An efficient palladium-catalyzed aerobic alkenylhydroxylation cyclization of allenamide derivatives was developed. Mechanistic studies indicated that the reaction might undergo a radical process.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Key Technology Research and Development Program of Shandong

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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