Glycoengineering artificial receptors for microglia to phagocytose Aβ aggregates
Author:
Affiliation:
1. Laboratory of Chemical Biology
2. State Key Laboratory of Rare Earth Resource Utilization
3. Changchun Institute of Applied Chemistry
4. Chinese Academy of Sciences
5. Changchun
Abstract
A combination of metabolic glycoengineering and self-triggered click chemistry is utilized to engineer a microglial membrane with ThS as artificial Aβ receptors to promote microglia to phagocytose Aβ aggregates.
Funder
Chinese Academy of Sciences
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/SC/D0SC07067J
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