Affiliation:
1. Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA
Abstract
The synthesis of pseudouridimycin, a potent and selective bacterial RNA polymerase inhibitor, is reported. Decomposition studies revealed key chemical liabilities that informed the design of analogues with improved stability.
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis
Cited by
6 articles.
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