Conjugation of a GM3 lactone mimetic on carbon nanotubes enhances the related inhibition of melanoma-associated metastatic events

Author:

Arosio Paolo1234ORCID,Comito Giuseppina56789ORCID,Orsini Francesco1234ORCID,Lascialfari Alessandro1234ORCID,Chiarugi Paola56789ORCID,Ménard-Moyon Cécilia1011121314ORCID,Nativi Cristina158164ORCID,Richichi Barbara158164ORCID

Affiliation:

1. Department of Physics and INSTM

2. University of Milano

3. 20133 Milan

4. Italy

5. Department of Experimental and Clinical Biomedical Sciences

6. Biochemistry

7. Human Health Medical School

8. University of Florence

9. 50134 Firenze

10. University of Strasbourg

11. CNRS

12. Immunology

13. Immunopathology and Therapeutic Chemistry

14. 67000 Strasbourg

15. Department of Chemistry “Ugo Schiff”

16. 50019 Sesto F.no

Abstract

Carbon nanotubes conjugated to a mimetic of a melanoma-associated antigen interfere with adhesion, motility, and invasiveness of human melanoma cells.

Funder

Centre National de la Recherche Scientifique

European Cooperation in Science and Technology

Università degli Studi di Milano

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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