Nano-clustering of ligands on surrogate antigen presenting cells modulates T cell membrane adhesion and organization
Author:
Affiliation:
1. Aix-Marseille Université
2. CNRS
3. CINaM-UMR 7325
4. Marseille
5. France
6. Laboratoire Adhésion & Inflammation Aix-Marseille Université\Inserm U1067\CNRS-UMR7333
7. Marseille 13288
Abstract
Artificial antigen presenting cells with clustered T cell ligands were prepared and used to reveal a dual scale of T cell response: a local nano-scale response in which the cell redistributes key signalling molecules, and a global cell scale response according to the average ligand density.
Funder
Agence Nationale de la Recherche
European Research Council
Publisher
Oxford University Press (OUP)
Subject
Biochemistry,Biophysics
Link
http://pubs.rsc.org/en/content/articlepdf/2016/IB/C5IB00293A
Reference72 articles.
1. Receptor Signaling Clusters in the Immune Synapse
2. Building a patchwork — The yeast plasma membrane as model to study lateral domain formation
3. Adhesion-mediated mechanosensitivity: a time to experiment, and a time to theorize
4. Integrin-Matrix Clusters Form Podosome-like Adhesions in the Absence of Traction Forces
5. Three-dimensional segregation of supramolecular activation clusters in T cells
Cited by 15 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Bioinspired Materials for Immunoengineering of T Cells and Natural Killer Cells;Advanced Functional Materials;2023-09-13
2. The T cell receptor displays lateral signal propagation involving non-engaged receptors;Nanoscale;2022
3. Ligand Nanocluster Array Enables Artificial-Intelligence-Based Detection of Hidden Features in T-Cell Architecture;Nano Letters;2021-06-25
4. Molecular Biomechanics Controls Protein Mixing and Segregation in Adherent Membranes;International Journal of Molecular Sciences;2021-04-02
5. Large-Area Biomolecule Nanopatterns on Diblock Copolymer Surfaces for Cell Adhesion Studies;Nanomaterials;2019-04-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3