Acid-mediated sulfonylation of arylethynylene bromides with sodium arylsulfinates: synthesis of (E)-1,2-bis(arylsulfonyl)ethylenes and arylacetylenic sulfones-Reference-Cited by-同舟云学术

Acid-mediated sulfonylation of arylethynylene bromides with sodium arylsulfinates: synthesis of (E)-1,2-bis(arylsulfonyl)ethylenes and arylacetylenic sulfones

Published:2017 Issue:57 Volume:7 Page:36112-36116
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Dai Chenshu¹²³⁴⁵,Wang Junqi¹²³⁴⁵,Deng Siqi¹²³⁴⁵,Zhou Candong¹²³⁴⁵,Zhang Wenhe¹²³⁴⁵,Zhu Qiuhua¹²³⁴⁵^ORCID,Tang Xiaodong¹²³⁴⁵^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of New Drug Screening

2. School of Pharmaceutical Sciences

3. Southern Medical University

4. Guangzhou 510515

5. P. R. China

Abstract

A solvent-dependent sulfonylation of arylethynylene bromides with sodium arylsulfinates to afford (E)-1,2-bis(arylsulfonyl)ethylenes and arylacetylenic sulfones is described.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA07105A

Reference58 articles.

1. Vinyl Sulfone-Based Peptidomimetics as Anti-Trypanosomal Agents: Design, Synthesis, Biological and Computational Evaluation

2. Discovery of Cyclic Sulfone Hydroxyethylamines as Potent and Selective β-Site APP-Cleaving Enzyme 1 (BACE1) Inhibitors: Structure-Based Design and in Vivo Reduction of Amyloid β-Peptides

3. Activity-based fingerprinting and inhibitor discovery of cysteine proteases in a microarray

4. Design, Synthesis, and Biological Evaluation of Sulfonyl Acrylonitriles as Novel Inhibitors of Cancer Metastasis and Spread

5. Synthesis of 1-Aryltetralins and 1-Arylnaphthalenes via (4 + 2) Annulation of β-Ketosulfones with Styryl Bromides

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