Saffron extract (Safr'Inside™) improves anxiety related behaviour in a mouse model of low-grade inflammation through the modulation of the microbiota and gut derived metabolites-Reference-Cited by-同舟云学术

Saffron extract (Safr'Inside™) improves anxiety related behaviour in a mouse model of low-grade inflammation through the modulation of the microbiota and gut derived metabolites

Published:2022 Issue:23 Volume:13 Page:12219-12233
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Pontifex Matthew G.¹,Connell Emily¹,Le Gall Gwenaelle¹,Pourtau Line²,Gaudout David²,Angeloni Cristina³,Zallocco Lorenzo⁴^ORCID,Ronci Maurizio⁵,Giusti Laura⁶,Müller Michael¹,Vauzour David¹^ORCID

Affiliation:

1. Norwich Medical School, Faculty of Medicine and Health Sciences, University of East Anglia, Norwich NR4 7TJ, UK

2. Activ'Inside, Beychac et Caillau, France

3. Department for Life Quality Studies, Alma Mater Studiorum, University of Bologna, Corso d'Augusto 237, 47921 Rimini, RN, Italy

4. Department of Pharmacy, University of Pisa, 56126 Pisa, Italy

5. Department of Pharmacy, University G. d'Annunzio of Chieti-Pescara, Chieti, Italy

6. School of Pharmacy, University of Camerino, Via Gentile III da Varano, 62032 Camerino, MC, Italy

Abstract

Treatment of anxiety and depression predominantly centres around pharmacological interventions, which have faced criticism for their associated side effects, lack of efficacy and low tolerability.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D2FO02739A

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