Novel α-ketoamide based diazeniumdiolates as hydrogen peroxide responsive nitric oxide donors with anti-lung cancer activity-Reference-Cited by-同舟云学术

Novel α-ketoamide based diazeniumdiolates as hydrogen peroxide responsive nitric oxide donors with anti-lung cancer activity

Published:2019 Issue:86 Volume:55 Page:12904-12907
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Fu Junjie¹²³⁴⁵^ORCID,Han Jing⁶⁷⁸⁹¹⁰^ORCID,Meng Tingting¹²³⁴⁵,Hu Jing¹²³⁴⁵,Yin Jian¹²³⁴⁵

Affiliation:

1. Key Laboratory of Carbohydrate Chemistry and Biotechnology

2. Ministry of Education

3. School of Biotechnology

4. Jiangnan University

5. Wuxi 214122

6. School of Chemistry & Materials Science

7. Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials

8. Jiangsu Normal University

9. Xuzhou 221116

10. P. R. China

Abstract

Novel α-ketoamide based diazeniumdiolates activated by hydrogen peroxide to release nitric oxide and exert anti-cancer activity.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C9CC05266F

Reference29 articles.

1. Nitric Oxide Donor-Based Cancer Therapy: Advances and Prospects

2. Fifty Years of Diazeniumdiolate Research. From Laboratory Curiosity to Broad-Spectrum Biomedical Advances

3. Targeting Nitric Oxide (NO) Delivery in Vivo. Design of a Liver-Selective NO Donor Prodrug That Blocks Tumor Necrosis Factor-α-Induced Apoptosis and Toxicity in the Liver

4. O2-3-Aminopropyl diazeniumdiolates suppress the progression of highly metastatic triple-negative breast cancer by inhibition of microvesicle formation via nitric oxide-based epigenetic regulation

5. Glycosylated diazeniumdiolates: a novel class of enzyme-activated nitric oxide donors

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