Novel α-ketoamide based diazeniumdiolates as hydrogen peroxide responsive nitric oxide donors with anti-lung cancer activity

Author:

Fu Junjie12345ORCID,Han Jing678910ORCID,Meng Tingting12345,Hu Jing12345,Yin Jian12345

Affiliation:

1. Key Laboratory of Carbohydrate Chemistry and Biotechnology

2. Ministry of Education

3. School of Biotechnology

4. Jiangnan University

5. Wuxi 214122

6. School of Chemistry & Materials Science

7. Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials

8. Jiangsu Normal University

9. Xuzhou 221116

10. P. R. China

Abstract

Novel α-ketoamide based diazeniumdiolates activated by hydrogen peroxide to release nitric oxide and exert anti-cancer activity.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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