Targeting Nitric Oxide (NO) Delivery in Vivo. Design of a Liver-Selective NO Donor Prodrug That Blocks Tumor Necrosis Factor-α-Induced Apoptosis and Toxicity in the Liver-Reference-Cited by-同舟云学术

Targeting Nitric Oxide (NO) Delivery in Vivo. Design of a Liver-Selective NO Donor Prodrug That Blocks Tumor Necrosis Factor-α-Induced Apoptosis and Toxicity in the Liver

Published:1997-06-01 Issue:13 Volume:40 Page:1947-1954
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Saavedra Joseph E.¹,Billiar Timothy R.¹,Williams Debra L.¹,Kim Young-Myeong¹,Watkins Simon C.¹,Keefer Larry K.¹

Affiliation:

1. Intramural Research Support Program, SAIC Frederick, NCI-FCRDC, Frederick, Maryland 21702, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15261, and Chemistry Section, Laboratory of Comparative Carcinogenesis, National Cancer Institute, Frederick Cancer Research and Development Center, Frederick, Maryland 21702

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9701031

Reference43 articles.

1. Nitric Oxide: A New Paradigm for Second Messengers

2. Localizing Antithrombotic and Vasodilatory Activity with a Novel, Ultrafast Nitric Oxide Donor

3. S-Nitrosothiol detection

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