Isothiourea-catalysed enantioselective annulation of 2-aminobenzothiophenes with α,β-unsaturated anhydrides-Reference-Cited by-同舟云学术

Isothiourea-catalysed enantioselective annulation of 2-aminobenzothiophenes with α,β-unsaturated anhydrides

Published:2022 Issue:20 Volume:9 Page:5551-5556
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Niu Cheng¹,Xie Dong-Hua¹,Du Da-Ming¹^ORCID

Affiliation:

1. Key Laboratory of Medical Molecule Science & Pharmaceutics Engineering (Ministry of Industry and Information Technology), School of Chemistry and Chemical Engineering, Beijing Institute of Technology, No. 5 Zhongguancun South Street, Beijing 100081, People's Republic of China

Abstract

An isothiourea-catalysed asymmetric Michael/lactamization cascade reaction of 2-aminobenzothiophenes and α,β-unsaturated anhydrides for the enantioselective synthesis of benzothienopiperidones with high stereoselectivities was developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO01023B

Reference29 articles.

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