Inhibition of apoptosis and biofilm formation in Candida auris by click-synthesized triazole-bridged quinoline derivatives

Author:

Wani Mohmmad Younus1ORCID,Srivastava Vartika2ORCID,El-Said Waleed Ahmed1ORCID,Al-Bogami Abdullah Saad1,Ahmad Aijaz23ORCID

Affiliation:

1. Department of Chemistry, College of Science, University of Jeddah, 21589 Jeddah, Saudi Arabia

2. Department of Clinical Microbiology and Infectious Diseases, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, South Africa

3. Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, 15213, USA

Abstract

Candida auris, a recent addition to the Candida species, poses a significant threat with its association to numerous hospital outbreaks globally, particularly affecting immunocompromised individuals.

Funder

University of Jeddah

Publisher

Royal Society of Chemistry (RSC)

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