Phase-transfer catalyzed Michael/ammonolysis cascade reactions of enaminones and olefinic azlactones: a new approach to structurally diverse quinoline-2,5-diones

Abstract

A Michael/ammonolysis cascade reaction of enaminones and olefinic azlactones via phase-transfer catalysis has been developed, which provides rapid access to a diverse set of quinoline-2,5-diones bearing a secondary amide group at the C-3 position.