Rapid determination of rebaudioside A content in the macroporous resin elution process using a portable near-infrared spectrometer-Reference-Cited by-同舟云学术

Rapid determination of rebaudioside A content in the macroporous resin elution process using a portable near-infrared spectrometer

Published:2023 Issue:45 Volume:47 Page:20920-20927
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Gao Lele¹,Wang Difan¹,Zhong Liang¹,Yue Jianan¹,Nie Lei¹^ORCID,Li Lian¹^ORCID,Meng Zhaoqing²,Cao Guiyun²,Lai Yuqiang³,Zang Hengchang¹⁴⁵^ORCID

Affiliation:

1. NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China

2. Shandong Hongjitang Pharmaceutical Group Co. Ltd, Jinan, 250103, China

3. Shandong Qufu Shengren Pharmaceutical Co. Ltd., Jining, 273100, China

4. National Glycoengineering Research Center, Shandong University, Jinan, 250012, China

5. Key Laboratory of Chemical Biology (Ministry of Education), Shandong University, Jinan, 250012, China

Abstract

Portable NIR spectroscopy is used to monitor the macroporous resin elution process. The PLSR and SVMR models displayed good performance for determining the RA content. The PLSR model displayed higher predictive accuracy than the SVMR model.

Funder

Key Technology Research and Development Program of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D3NJ04042A

Reference43 articles.

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