β-Sitosterol and stigmasterol ameliorate dextran sulfate sodium-induced colitis in mice fed a high fat Western-style diet-Reference-Cited by-同舟云学术

β-Sitosterol and stigmasterol ameliorate dextran sulfate sodium-induced colitis in mice fed a high fat Western-style diet

Published:2017 Issue:11 Volume:8 Page:4179-4186
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Feng Simin¹²³⁴⁵,Dai Zhuqing¹²³⁴⁵,Liu Anna¹²³⁴⁵,Wang Hong¹²³⁴⁵^ORCID,Chen Jayson¹²³⁴⁵,Luo Zisheng⁶⁷⁸⁹,Yang Chung S.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemical Biology

2. Ernest Mario School of Pharmacy

3. Rutgers

4. the State University of New Jersey

5. Piscataway

6. Department of Food Science and Nutrition

7. Zhejiang University

8. Hangzhou 310058

9. People's Republic of China

Abstract

Stigmasterol and β-sitosterol ameliorate DSS-induced colitis in mice by suppressing the activation of NF-κB; stigmasterol also downregulates COX-2 and CSF-1.

Funder

Center for Scientific Review

Rutgers, The State University of New Jersey

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2017/FO/C7FO00375G

Reference37 articles.

1. Ketosteroids and hydroxyketosteroids, minor metabolites of sugarcane wax

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3. Analysis of phytosterols in foods

4. Injected phytosterols/stanols suppress plasma cholesterol levels in hamsters

5. β-Sitosterol attenuates high-fat diet-induced intestinal inflammation in mice by inhibiting the binding of lipopolysaccharide to toll-like receptor 4 in the NF-κB pathway

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