A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent-Reference-Cited by-同舟云学术

A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent

Published:2021 Issue:1 Volume:19 Page:156-161
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Anselmi Silvia¹²³⁴^ORCID,Liu Siyu¹²³⁴^ORCID,Kim Seong-Heun¹²³⁴^ORCID,Barry Sarah M.⁵⁶²⁴^ORCID,Moody Thomas S.⁷⁸⁹⁴¹⁰^ORCID,Castagnolo Daniele¹²³⁴^ORCID

Affiliation:

1. School of Cancer and Pharmaceutical Sciences

2. King's College London

3. London

4. UK

5. Department of Chemistry

6. Faculty of Natural & Mathematical Sciences

7. Almac Sciences

8. Department of Biocatalysis & Isotope Chemistry

9. Craigavon

10. Arran Chemical Company Limited

Abstract

Sulfoxides have been synthesised from various sulfide substrates under mild conditions exploiting CALB biocatalyst in the presence of urea hydrogen peroxide and AcOEt which acts with the dual role of solvent and reagent.

Funder

Biotechnology and Biological Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D0OB01966F

Reference71 articles.

1. Recent Applications in the Use of Sulfoxides as Chiral Auxiliaries for the Asymmetric Synthesis of Natural and Biologically Active Products

2. Enantioselective Approach to Polyhydroxylated Compounds Using Chiral Sulfoxides: Synthesis of Enantiomerically Pure myo-Inositol and Pyrrolidine Derivatives

3. Transition Metal‐Catalyzed C−H Bond Functionalizations by Use of Sulfur‐Containing Directing Groups