Linear free energy relationships in RNA transesterification: theoretical models to aid experimental interpretations
Author:
Affiliation:
1. Scientific Computation
2. University of Minnesota
3. Minneapolis, USA
4. Center for Integrative Proteomics Research
5. BioMaPS Institute and Department of Chemistry & Chemical Biology
6. Rutgers University
7. Piscataway, USA
Abstract
Depending on the nature of the leaving group, reactions may proceedviaa stepwise mechanism or through a single early TS1. Brønsted correlations can be used to distinguish these two mechanisms.
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2014/CP/C4CP01050G
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