Real-time neurochemical measurement of dynamic metabolic events during cardiac arrest and resuscitation in a porcine model

Author:

Gowers Sally A. N.123ORCID,Samper Isabelle C.123ORCID,Murray De-Shaine R. K.123ORCID,Smith Georgia K.123,Jeyaprakash Sarah123,Rogers Michelle L.123ORCID,Karlsson Michael4567,Olsen Markus Harboe8567,Møller Kirsten8567,Boutelle Martyn G.123ORCID

Affiliation:

1. Department of Bioengineering

2. Imperial College London

3. UK

4. Department of Neurosurgery

5. Rigshospitalet

6. Copenhagen

7. Denmark

8. Department of Neuroanaesthesiology

Abstract

This work describes a fully-integrated portable microfluidic analysis system for real-time monitoring of dynamic changes in glucose and lactate occurring in the brain as a result of cardiac arrest and resuscitation.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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