Stereoselective organocatalyzed glycosylations – thiouracil, thioureas and monothiophthalimide act as Brønsted acid catalysts at low loadings
Author:
Affiliation:
1. Centre for Synthesis & Chemical Biology
2. UCD School of Chemistry
3. University College Dublin
4. Dublin 4
5. Ireland
Abstract
Thiouracil catalyzes stereoselective glycosylations with galactals in loadings as low as 0.1 mol%.
Funder
Irish Research Council
Science Foundation Ireland
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/SC/C8SC02788A
Reference94 articles.
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2. K. Hof , K. M.Lippert and P. R.Schreiner in Asymmetric Organocatalysis , ed. K. Maruoka ), Thieme , Stuttgart , 2012 , ch. 2.2.4, vol. 2
3. Small-Molecule H-Bond Donors in Asymmetric Catalysis
4. Theoretical Studies on the Bifunctionality of Chiral Thiourea-Based Organocatalysts: Competing Routes to C−C Bond Formation
5. Enantioselective Michael Reaction of Malonates to Nitroolefins Catalyzed by Bifunctional Organocatalysts
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