Design, synthesis and anti-proliferative activities of novel 7′-O-substituted schisantherin A derivatives-Reference-Cited by-同舟云学术

Design, synthesis and anti-proliferative activities of novel 7′-O-substituted schisantherin A derivatives

Published:2016 Issue:6 Volume:7 Page:1159-1170
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Venkanna A.¹²³⁴⁵,Kumar Ch. Pavan¹²³⁴⁵,Poornima B.¹²³⁴⁵,Siva Bandi¹²³⁴⁵,Jain Nishant⁶³⁴⁵,Suresh Babu K.¹²³⁴⁵

Affiliation:

1. Natural Products Laboratory

2. Division of Natural Products Chemistry

3. CSIR-Indian Institute of Chemical Technology

4. Hyderabad 500 007

5. India

6. Centre for Chemical Biology

Abstract

A series of schisantherin A (1) derivatives were efficiently synthesized utilizing Yamaguchi esterification (2,4,6-trichlorobenzoyl chloride, Et₃N, THF, DMAP, toluene) at the C-7′ position of the schisantherin A core.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00097E

Reference24 articles.

1. Cancer Control Opportunities in Low- and Middle-income Countries

2. Impact of Natural Products on Developing New Anti-Cancer Agents

3. Heat shock proteins in the regulation of apoptosis: new strategies in tumor therapy

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