High-specificity double-stranded DNA detection with a “humanoid” molecular beacon and TALEs

Author:

Wang Yu12345ORCID,Bai Jialei12345,Qu Xiaochen12345,Gao Yifei6789,Wang Jiang12345,Li Shuang12345,Fan Longxing12345,Wei Haiping10111213,Liu Sha12345,Peng Yuan12345,Gao Zihan12345,Zhu Yulin12345,Gao Zhixian12345,Ning Baoan12345

Affiliation:

1. Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety

2. Institute of Environmental and Operational Medicine

3. Academy of Military Medical Science

4. Academy of Military Science

5. Tianjin 300050

6. School of Chemistry

7. University of New South Wales

8. Sydney

9. Australia

10. School of Tourism Management

11. Tianjin Vocational Institute

12. Tianjin 300350

13. P.R. China

Abstract

Ultra-sensitive and high-specificity detection of dsDNA based on TALEs-specific recognition of DNA properties and H-MB fluorescence signal output capability.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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