Single-molecule nanopore sensing of actin dynamics and drug binding-Reference-Cited by-同舟云学术

Single-molecule nanopore sensing of actin dynamics and drug binding

Published:2020 Issue:4 Volume:11 Page:970-979
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Wang Xiaoyi¹²³⁴^ORCID,Wilkinson Mark D.¹²³⁴^ORCID,Lin Xiaoyan¹²³⁴^ORCID,Ren Ren¹²³⁴^ORCID,Willison Keith R.¹²³⁴^ORCID,Ivanov Aleksandar P.¹²³⁴^ORCID,Baum Jake⁵²⁶⁴^ORCID,Edel Joshua B.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Imperial College London

3. Molecular Sciences Research Hub

4. UK

5. Department of Life Sciences

6. London SW7 2AZ

Abstract

Nanopipettes were used for real-time investigation into actin dynamics and drug binding at single-molecule resolution, showing promise for a better understanding of the mechanism of protein–protein interactions and drug discovery.

Funder

Engineering and Physical Sciences Research Council

Biotechnology and Biological Sciences Research Council

Wellcome Trust

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/C9SC05710B

Reference50 articles.

1. Actin Structure and Function