Enhancements in the utilization of antigene oligonucleotides in the nucleus by booster oligonucleotides-Reference-Cited by-同舟云学术

Enhancements in the utilization of antigene oligonucleotides in the nucleus by booster oligonucleotides

Published:2020 Issue:67 Volume:56 Page:9731-9734
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Wang Lei¹²³⁴,Okamura Hidenori¹²³⁴,Sasaki Shigeki¹²³⁴^ORCID,Taniguchi Yosuke¹²³⁴^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences

2. Kyushu University

3. Fukuoka

4. Japan

Abstract

Oligonucleotides containing dU, which are called booster oligonucleotides, are excised by uracil-DNA glycosylase in the nucleus and efficiently release complementary strands.

Funder

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Mochida Memorial Foundation for Medical and Pharmaceutical Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/D0CC04240D

Reference24 articles.

1. Oligonucleotide therapeutics: chemistry, delivery and clinical progress

2. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide.

3. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

4. Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase

5. In vitro selection of RNA molecules that bind specific ligands

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