Inhibition of transcription and antiproliferative effects in a cancer cell line using antigene oligonucleotides containing artificial nucleoside analogues-Reference-Cited by-同舟云学术

Inhibition of transcription and antiproliferative effects in a cancer cell line using antigene oligonucleotides containing artificial nucleoside analogues

Published:2023 Issue:8 Volume:14 Page:1482-1491
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Wang Lei¹²^ORCID,Notomi Ryotaro¹,Sasaki Shigeki¹³^ORCID,Taniguchi Yosuke¹^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan

2. School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong 226001, PR China

3. Graduate School of Pharmaceutical Sciences, Nagasaki International University, 2825-7 Huis Ten Bosch Machi, Sasebo City, Nagasaki 859-3298, Japan

Abstract

Antigene TFOs having artificial nucleoside analogues were synthesized and examined for their antigene and antiproliferative effects on living cells, showing that they have stronger cell growth inhibitory effects than natural type antigene ODNs.

Funder

Japan Society for the Promotion of Science

Japan Science and Technology Agency

Nantong University

Japan Agency for Medical Research and Development

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/MD/D3MD00139C

Reference44 articles.