The role of morphology, shell composition and protein corona formation in Au/Fe3O4 composite nanoparticle mediated macrophage responses

Author:

He Lihua1,Ma Kang1,Liu Xiaonan1ORCID,Li Huixia1,Zhang Lei2,Tian Miaomiao3,Tian Zuhong3,Qiang Yujie1,Cui Yali145ORCID,Hua Kai14ORCID

Affiliation:

1. College of Life Sciences, Northwest University, Xi’an, 710069, China

2. Key Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710119, China

3. State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi’an, 710032, China

4. Shaanxi Provincial Engineering Research Center for Nano-Biomedical Detection, Xi'an, 710077, China

5. Institute of Deep Medicine, Northwest University, Xi’an, 710069, China

Abstract

Addressing the nanoparticle-mediated macrophage response profile associated with Au/Fe3O4 composite nanoparticle morphology, shell composition and protein corona patterns.

Funder

National Natural Science Foundation of China

Swedish Foundation for International Cooperation in Research and Higher Education

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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