Electrostatic assembly of gold nanoparticle and metal–organic framework nanoparticles attenuates amyloid β aggregate-mediated neurotoxicity-Reference-Cited by-同舟云学术

Electrostatic assembly of gold nanoparticle and metal–organic framework nanoparticles attenuates amyloid β aggregate-mediated neurotoxicity

Published:2023 Issue:20 Volume:11 Page:4453-4463
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Yang Licong¹²,Chen Yutong¹,Jia Zhi¹,Yuan Xiaoyu¹,Liu Jie¹^ORCID

Affiliation:

1. Department of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China

2. College of Biological Science and Engineering, Fuzhou University, Fuzhou, 350108, China

Abstract

AuNPs@PEG@MIL-101 efficiently suppresses extracellular Aβ fibrillation, decreases intracellular Aβ40 aggregation, and finally protects PC12 cells from the cell membrane damage and microtubular defects induced by Aβ40 fibers.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D3TB00281K

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