A base promoted one pot solvent free version of the Ramachary reductive coupling/alkylation reaction for the synthesis of 2,2-disubstituted ethyl cyanoacetates-Reference-Cited by-同舟云学术

A base promoted one pot solvent free version of the Ramachary reductive coupling/alkylation reaction for the synthesis of 2,2-disubstituted ethyl cyanoacetates

Published:2018 Issue:16 Volume:8 Page:8961-8964
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Jiang Guangyou¹²³⁴,Liu Min¹²³⁴,Fang Dongmei⁵⁶³⁴,Tan Ping¹²³⁴,Huang Min¹²³⁴,Zhou Taiping¹²³⁴,Jiang Zhenju¹²³⁴,Xu Zhihong¹²³⁴,Wang Zhouyu¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Xihua University

3. Chengdu

4. China

5. Chengdu Institute of Biology

6. Chinese Academy of Sciences

Abstract

An N,N-diisopropylethylamine promoted solvent-free Ramachary reductive coupling/alkylation (RRC/A) reaction for the synthesis of 2,2-disubstituted ethyl cyanoacetates has been developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA00326B

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5. Reductive alkylation of active methylene compounds with carbonyl derivatives, calcium hydride and a heterogeneous catalyst

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