Self-sufficient asymmetric reduction of β-ketoesters catalysed by a novel and robust thermophilic alcohol dehydrogenase co-immobilised with NADH-Reference-Cited by-同舟云学术

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Self-sufficient asymmetric reduction of β-ketoesters catalysed by a novel and robust thermophilic alcohol dehydrogenase co-immobilised with NADH

Published:2021 Issue:9 Volume:11 Page:3217-3230
ISSN:2044-4753
Container-title:Catalysis Science & Technology
language:en
Short-container-title:Catal. Sci. Technol.

Author:

Orrego Alejandro H.¹²³⁴⁵^ORCID,Andrés-Sanz Daniel⁶⁷⁸⁹⁵^ORCID,Velasco-Lozano Susana⁶⁷⁸⁹⁵,Sanchez-Costa Mercedes¹⁰¹¹¹²⁴⁵,Berenguer José¹⁰¹¹¹²⁴⁵,Guisan José M.¹²³⁴⁵^ORCID,Rocha-Martin Javier¹²³⁴⁵^ORCID,López-Gallego Fernando⁶⁷⁸⁹⁵^ORCID

Affiliation:

1. Department of Biocatalysis

2. Institute of Catalysis and Petrochemistry (ICP)

3. CSIC

4. 28049 Madrid

5. Spain

6. Heterogeneous Biocatalysis Laboratory

7. Center for Cooperative Research in Biomaterials (CIC biomaGUNE)

8. Basque Research and Technology Alliance (BRTA)

9. Donostia San Sebastián

10. Department of Molecular Biology

11. Universidad Autónoma de Madrid

12. Center for Molecular Biology Severo-Ochoa (UAM-CSIC)

Abstract

A highly robust and productive self-sufficient heterogeneous biocatalysts to asymmetrically reduce β-ketoesters.

Funder

Ikerbasque, Basque Foundation for Science

H2020 Future and Emerging Technologies

H2020 European Research Council

Ministerio de Ciencia e Innovación

Fundación Ramón Areces

Publisher

Royal Society of Chemistry (RSC)

Subject

Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CY/D1CY00268F

Reference62 articles.

1. A review—biosynthesis of optically pure ethyl (S)-4-chloro-3-hydroxybutanoate ester: recent advances and future perspectives

2. Efficient biocatalytic stereoselective reduction of methyl acetoacetate catalyzed by whole cells of engineered E. coli

3. New opportunities for biocatalysis: driving the synthesis of chiral chemicals

4. Asymmetric biocatalysis with microbial enzymes and cells

5. Biocatalysis: applications and potentials for the chemical industry

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