DNA nanomachine for visual detection of structured RNA and double stranded DNA-Reference-Cited by-同舟云学术

DNA nanomachine for visual detection of structured RNA and double stranded DNA

Published:2022 Issue:35 Volume:58 Page:5395-5398
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Gorbenko Daria A.¹²,Shkodenko Liubov A.¹,Rubel Maria S.¹,Slita Aleksandr V.³,Nikitina Ekaterina V.⁴,Martens Elvira A.⁴^ORCID,Kolpashchikov Dmitry M.¹⁵⁶⁷^ORCID

Affiliation:

1. Laboratory of Molecular Robotics and Biosensor Materials, SCAMT Institute, ITMO University, Saint-Petersburg, Russia, 9 Lomonosova Str., St. Petersburg, 191002, Russian Federation

2. Ioffe Institute, 26 Politekhnicheskaya, St. Petersburg, 194021, Russian Federation

3. St. Petersburg Pasteur Institute, 14 Mira Str., St. Petersburg, 197101, Russian Federation

4. Pediatric Research and Clinical Center for Infectious Diseases, 9 Prof. Popova Str, Saint Petersburg, 197022, Russian Federation

5. Chemistry Department, University of Central Florida, 4000 Central Florida Blvd., Orlando, FL 32816, USA

6. Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, USA

7. National Center for Forensic Science, University of Central Florida, Orlando, FL, USA

Abstract

A DNA machine (PxDm) binds a tightly folded RNA analyte via Arms 2 and 3. Arm 1 hybridizes with high selectivity to form a G-quadruplex, which changes the solution color.

Funder

ITMO University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D2CC00325B

Reference41 articles.

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