Advanced continuous-flow microfluidic device for parallel screening of crystal polymorphs, morphology, and kinetics at controlled supersaturation-Reference-Cited by-同舟云学术

Advanced continuous-flow microfluidic device for parallel screening of crystal polymorphs, morphology, and kinetics at controlled supersaturation

Published:2021 Issue:12 Volume:21 Page:2333-2342
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Coliaie Paria¹²³⁴,Kelkar Manish S.⁵⁶⁷⁴,Langston Marianne⁸⁹¹⁰⁴,Liu Chengxiang¹¹¹⁰⁴,Nazemifard Neda¹²⁹¹⁰⁴,Patience Daniel¹¹¹⁰⁴,Skliar Dimitri¹²¹³¹⁴⁴,Nere Nandkishor K.¹²³⁴⁵,Singh Meenesh R.¹²³⁴^ORCID

Affiliation:

1. Department of Chemical Engineering

2. University of Illinois at Chicago

3. Chicago

4. USA

5. Center of Excellence for Isolation & Separation Technologies (CoExIST)

6. Process R&D, AbbVie Inc.

7. North Chicago

8. Pharmaceutics Research – Analytical Development

9. Takeda Pharmaceuticals International Co.

10. Cambridge

11. Pharmaceutical Development

12. Chemical Process Development

13. Product Development, Bristol Myers Squibb Co.

14. New Brunswick

Abstract

An advanced continuous-flow microfluidic device for rapid, parallel screening of crystalline materials, which can profoundly impact the discovery and development of active pharmaceutical ingredients and other crystalline materials.

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/LC/D1LC00218J

Reference21 articles.

1. Continuous-flow, well-mixed, microfluidic crystallization device for screening of polymorphs, morphology, and crystallization kinetics at controlled supersaturation

2. Microfluidic platforms: a mainstream technology for the preparation of crystals

3. Microfluidic Platforms toward Rational Material Fabrication for Biomedical Applications

4. Microfluidic technologies for accelerating the clinical translation of nanoparticles

5. A high-throughput label-free nanoparticle analyser

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