Recent developments in the total synthesis of natural products using the Ugi multicomponent reactions as the key strategy-Reference-Cited by-同舟云学术

Recent developments in the total synthesis of natural products using the Ugi multicomponent reactions as the key strategy

Published:2024 Issue:3 Volume:22 Page:429-465
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Larghi Enrique L.¹^ORCID,Bracca Andrea B. J.¹^ORCID,Simonetti Sebastián O.¹^ORCID,Kaufman Teodoro S.¹^ORCID

Affiliation:

1. Instituto de Química Rosario (IQUIR, CONICET-UNR) and Facultad de Ciencias Bioquímicas y Farmacéuticas – Universidad Nacional de Rosario, Suipacha 531 (2000), Rosario, Argentina

Abstract

The Ugi multicomponent reaction has acquired a prominent place in modern total synthesis of natural products. Their simplicity and versatility have enabled the development of elegant, efficient, and step-economical sequences toward complex compounds.

Funder

Consejo Nacional de Investigaciones Científicas y Técnicas

Fondo para la Investigación Científica y Tecnológica

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D3OB01837G

Reference391 articles.

1. Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

2. Bridging the gap between natural product synthesis and drug discovery