Ketogenic diet aggravates colitis, impairs intestinal barrier and alters gut microbiota and metabolism in DSS-induced mice-Reference-Cited by-同舟云学术

Ketogenic diet aggravates colitis, impairs intestinal barrier and alters gut microbiota and metabolism in DSS-induced mice

Published:2021 Issue:20 Volume:12 Page:10210-10225
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Li Shengjie¹²,Zhuge Aoxiang¹²,Wang Kaicen¹²,Lv Longxian¹²^ORCID,Bian Xiaoyuan¹²,Yang Liya¹²,Xia Jiafeng¹²,Jiang Xianwan¹²,Wu Wenrui¹²,Wang Shuting¹²,Wang Qiangqiang¹²,Li Lanjuan¹²^ORCID

Affiliation:

1. State Key Laboratory for Diagnosis, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China

2. Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China

Abstract

A ketogenic diet was shown to aggravate DSS-induced colitis in mice by increasing intestinal and systemic inflammation, and disrupting the intestinal barrier, which results from modulated gut microbiota and metabolism.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO02288A

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