Design and development of multifunctional polyphosphoester-based nanoparticles for ultrahigh paclitaxel dual loading-Reference-Cited by-同舟云学术

Design and development of multifunctional polyphosphoester-based nanoparticles for ultrahigh paclitaxel dual loading

Published:2017 Issue:41 Volume:9 Page:15773-15777
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Zhang Fuwu¹²³⁴⁵,Khan Sarosh¹²³⁴⁵,Li Richen¹²³⁴⁵,Smolen Justin A.¹²³⁴⁵,Zhang Shiyi¹²³⁴⁵,Zhu Guizhi⁶⁷⁸⁹¹⁰,Su Lu¹²³⁴⁵,Jahnke Ashlee A.¹²³⁴⁵,Elsabahy Mahmoud¹²³⁴⁵,Chen Xiaoyuan⁶⁷⁸⁹¹⁰^ORCID,Wooley Karen L.¹²³⁴⁵^ORCID

Affiliation:

1. Departments of Chemistry

2. Chemical Engineering

3. and Materials Science and Engineering

4. Laboratory for Synthetic-Biologic Interactions

5. and Texas A&M Institute for Preclinical Studies

6. Laboratory of Molecular Imaging and Nanomedicine (LOMIN)

7. National Institute of Biomedical Imaging and Bioengineering (NIBIB)

8. National Institutes of Health (NIH)

9. Bethesda

10. USA

Abstract

Polyphosphoester-based nanoparticles are capable of loading paclitaxel chemically and physically, achieving ultrahigh equivalent paclitaxel aqueous concentrations.

Funder

Welch Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NR/C7NR05935C

Reference23 articles.

1. Abraxane®, a novel Cremophor®-free, albumin-bound particle form of paclitaxel for the treatment of advanced non-small-cell lung cancer

2. Improving Paclitaxel Delivery: In Vitro and In Vivo Characterization of PEGylated Polyphosphoester-Based Nanocarriers

3. Well-defined diblock brush polymer–drug conjugates for sustained delivery of paclitaxel