Well-defined diblock brush polymer–drug conjugates for sustained delivery of paclitaxel
Author:
Affiliation:
1. Department of Chemical and Biological Engineering
2. University at Buffalo
3. The State University of New York
4. Buffalo
5. USA
6. Institute for Lasers
7. Photonics and Biophotonics
8. and Department of Chemistry
Abstract
The synthesis, characterization and property studies of paclitaxel (PTXL)-containing brush polymer–drug conjugates (BPDCs) are presented and the influence of grafting structures of BPDCs on their assembly behaviour, drug release profile and therapeutic effects is discussed in this article.
Funder
Division of Materials Research
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2015/BM/C4BM00458B
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