Practical one-pot amidation of N-Alloc-, N-Boc-, and N-Cbz protected amines under mild conditions-Reference-Cited by-同舟云学术

Practical one-pot amidation of N-Alloc-, N-Boc-, and N-Cbz protected amines under mild conditions

Published:2021 Issue:26 Volume:11 Page:15890-15895
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Hong Wan Pyo¹²³⁴,Tran Van Hieu⁵⁶⁷⁸⁴,Kim Hee-Kwon⁵⁶⁷⁸⁴^ORCID

Affiliation:

1. School of Advanced Materials and Chemical Engineering

2. Daegu Catholic University

3. Gyeongsan-si

4. Republic of Korea

5. Department of Nuclear Medicine

6. Molecular Imaging & Therapeutic Medicine Research Center

7. Jeonbuk National University Medical School and Hospital

8. Jeonju

Abstract

One-pot efficient transformation of N-Alloc-, N-Boc-, and N-Cbz protected amines to amides was achieved by using 2-chloropyridine and trifluoromethanesulfonyl anhydride as well as Grignard reagent and MgCl₂.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA02242C

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5. The chemistry and biology of guanidine natural products

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