Protein degradation profile reveals dynamic nature of 20S proteasome small molecule stimulation
Author:
Affiliation:
1. Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University
2. West Lafayette
3. USA
4. Purdue Proteomics Facility, Bindley Bioscience Center and Department of Comparative Pathobiology, Purdue University
Abstract
Small molecule stimulators of the 20S core particle of the proteasome can lead to the degradation of a variety of protein substrates.
Funder
National Institute of General Medical Sciences
American Cancer Society
Purdue University Center for Cancer Research
Publisher
Royal Society of Chemistry (RSC)
Link
http://pubs.rsc.org/en/content/articlepdf/2021/CB/D0CB00191K
Reference32 articles.
1. STRUCTURE AND FUNCTIONS OF THE 20S AND 26S PROTEASOMES
2. The ubiquitin-proteasome system
3. Ubiquitin-independent proteasomal degradation
4. Regulating the 20S Proteasome Ubiquitin-Independent Degradation Pathway
5. Oxidative Stress-Mediated Regulation of Proteasome Complexes
Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Rpt5-Derived Analogs Stimulate Human Proteasome Activity in Cells and Degrade Proteins Forming Toxic Aggregates in Age-Related Diseases;International Journal of Molecular Sciences;2024-04-25
2. Discovery and Development of Cyclic Peptide Proteasome Stimulators;ChemBioChem;2023-12-15
3. High resolution structures define divergent and convergent mechanisms of archaeal proteasome activation;Communications Biology;2023-07-15
4. Minimal mechanistic component of HbYX-dependent proteasome activation that reverses impairment by neurodegenerative-associated oligomers;Communications Biology;2023-07-14
5. Proteasomal Stimulation by MK886 and Its Derivatives Can Rescue Tau-Induced Neurite Pathology;Molecular Neurobiology;2023-07-10
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3