Subcellular protein turnover in human neural progenitor cells revealed by correlative electron microscopy and nanoscale secondary ion mass spectrometry imaging-Reference-Cited by-同舟云学术

Subcellular protein turnover in human neural progenitor cells revealed by correlative electron microscopy and nanoscale secondary ion mass spectrometry imaging

Published:2024 Issue:9 Volume:15 Page:3311-3322
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Lork Alicia A.¹^ORCID,Rabasco Stefania¹,Ernst Carl²,du Toit André¹,Rizzoli Silvio O.³^ORCID,Phan Nhu T. N.¹^ORCID

Affiliation:

1. Department of Chemistry and Molecular Biology University of Gothenburg, SE-412 96 Gothenburg, Sweden

2. Human Genetics, McGill University, H4H1R3 Montreal, Canada

3. Department of Neuro- and Sensory Physiology, University Medical Center Göttingen, Center for Biostructural Imaging of Neurodegeneration, Göttingen, Germany

Abstract

Protein turnover is a critical process for accurate cellular function, in which damaged proteins in the cells are gradually replaced with newly synthesized ones.

Funder

Hasselbladstiftelsen

Deutsche Forschungsgemeinschaft

Vetenskapsrådet

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SC/D3SC05629E

Reference50 articles.

1. Mechanisms of altered protein turnover in chronic diseases: a review of human kinetic studies

2. Type 2 diabetes as a protein misfolding disease

3. Unfolding the role of protein misfolding in neurodegenerative diseases

4. Systematic analysis of protein turnover in primary cells

5. Local and global influences on protein turnover in neurons and glia

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