The synthesis and biological evaluation of virtually designed fluoroquinolone analogs against fluoroquinolone-resistantEscherichia coliintended for UTI treatment-Reference-Cited by-同舟云学术

The synthesis and biological evaluation of virtually designed fluoroquinolone analogs against fluoroquinolone-resistantEscherichia coliintended for UTI treatment

Published:2020 Issue:31 Volume:44 Page:13308-13318
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Balasubramaniyan Sakthivel¹²³⁴⁵^ORCID,Irfan Navabshan⁶⁷⁸⁹^ORCID,Senthilkumar Chinnaiyan¹⁰¹¹⁹,Umamaheswari Appavoo¹²³⁴⁵,Puratchikody Ayarivan¹²³⁴⁵^ORCID

Affiliation:

1. Drug Discovery and Development Research Group

2. Department of Pharmaceutical Technology

3. University College of Engineering

4. Anna University

5. BIT Campus

6. School of Pharmacy

7. B.S. Abdur Rahman Crescent Institute of Science & Technology

8. Chennai 600048

9. India

10. Central Leather Research Institute-CSIR

11. Chennai 600020

Abstract

Synthesis and evaluvate the supercoiling activity of the virtually screened novel fluoroquinolone analogs against fluoroquinolone-resistantEscherichia colifor the treatment of urinary tract infections (UTIs).

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NJ/D0NJ00657B

Reference37 articles.

1. Urinary tract infections: epidemiology, mechanisms of infection and treatment options

2. Fluoroquinolone and Third-Generation-Cephalosporin Resistance among Hospitalized Patients with Urinary Tract Infections Due to Escherichia coli: Do Rates Vary by Hospital Characteristics and Geographic Region?

3. Antimicrobial susceptibility of organisms causing community-acquired urinary tract infections in Gauteng Province, South Africa

4. Occurrence of single-point gyrA mutations among ciprofloxacin-susceptible Escherichia coli isolates causing urinary tract infections in Latin America

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