Nickel-catalyzed enantioselective vinylation of aryl 2-azaallyl anions-Reference-Cited by-同舟云学术

Nickel-catalyzed enantioselective vinylation of aryl 2-azaallyl anions

Published:2021 Issue:18 Volume:12 Page:6406-6412
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Duan Shengzu¹²³⁴⁵,Deng Guogang¹²³⁴⁵,Zi Yujin¹²³⁴⁵,Wu Xiaomei¹²³⁴⁵,Tian Xun¹²³⁴⁵,Liu Zhengfen¹²³⁴⁵,Li Minyan⁶⁷⁸⁹¹⁰,Zhang Hongbin¹²³⁴⁵^ORCID,Yang Xiaodong¹²³⁴⁵^ORCID,Walsh Patrick J.⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. Key Laboratory of Medicinal Chemistry for Natural Resource

2. Ministry of Education

3. Yunnan Provincial Center for Research & Development of Natural Products

4. School of Chemical Science and Technology

5. Yunnan University

6. Roy and Diana Vagelos Laboratories

7. Penn/Merck Laboratory for High-Throughput Experimentation

8. Department of Chemistry

9. University of Pennsylvania

10. Philadelphia

Abstract

A unique enantioselective Ni-catalyzed vinylation of 2-azaallyl anions is advanced. This method affords vinyl aryl methyl amine or 1,3-diamine derivatives with high enantioselectivities, which are frequently occurring scaffolds in medications.

Funder

National Science Foundation

National Basic Research Program of China

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Natural Science Foundation of Yunnan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC00972A