1. Aquatic Technology Research Center, Agricultural Technology Research Institute, Hsinchu 300, Taiwan
2. Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan
3. Division of Endocrinology, Department of Internal Medicine, Hsinchu Mackay Memorial Hospital, Hsinchu 300, Taiwan
4. Department of Chemical Engineering, Chung Yuan Christian University, Taoyuan City 320, Taiwan
5. Division of Pharmacy, Koo Foundation Sun Yat-Sen Cancer Center, Taipei 100, Taiwan
6. Center for Intelligent Drug Systems and Smart Bio-devices (IDS2B), National Chiao Tung University, Hsinchu 300, Taiwan