Evaluation of the efficacy of carbon nanotubes for delivering peptides into mitochondria-Reference-Cited by-同舟云学术

Evaluation of the efficacy of carbon nanotubes for delivering peptides into mitochondria

Published:2016 Issue:71 Volume:6 Page:67232-67241
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ficociello Graziella¹²³⁴,Salemme Adele⁵²³⁴,Uccelletti Daniela¹²³⁴,Fiorito Silvana⁶⁷⁴,Togna Anna Rita⁵²³⁴,Vallan Lorenzo⁸⁹¹⁰¹¹⁴,González-Domínguez Jose M.⁸⁹¹⁰¹¹⁴,Da Ros Tatiana⁸⁹¹⁰¹¹⁴,Francisci Silvia¹²³⁴,Montanari Arianna¹²³⁴¹²

Affiliation:

1. Department of Biology and Biotechnologies “Charles Darwin”

2. Sapienza University of Rome

3. 5-00185 Rome

4. Italy

5. Department of Physiology and Pharmacology “Vittorio Erspamer”

6. Institute of Translational Pharmacology – CNR

7. 100-00133 Rome

8. INSTM Unit of Trieste

9. Department of Chemical and Pharmaceutical Sciences

10. University of Trieste

11. 1-34127 Trieste

12. Pasteur Institute – Cenci Bolognetti Foundation

Abstract

Future therapy for mitochondrial pathologies: CKKSFLSPRTALINFLVK peptide from mitochondrial-LeuRS has a mitochondrial targeting activity when conjugated with multi-walled carbon nanotubes.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA14254K

Reference36 articles.

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2. Can yeast be used to study mitochondrial diseases? Biolistic tRNA mutants for the analysis of mechanisms and suppressors

3. Aminoacyl-tRNA synthetases are multivalent suppressors of defects due to human equivalent mutations in yeast mt tRNA genes

4. Structural and functional role of bases 32 and 33 in the anticodon loop of yeast mitochondrial tRNAIle

5. The yeast model suggests the use of short peptides derived from mt LeuRS for the therapy of diseases due to mutations in several mt tRNAs

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