Defluorinative functionalization of perfluoroalkyl alkenes with ureas: synthesis of <i>C</i>4-perfluoroalkenyl 2-imidazolones-Reference-Cited by-同舟云学术

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Defluorinative functionalization of perfluoroalkyl alkenes with ureas: synthesis of C4-perfluoroalkenyl 2-imidazolones

Published:2024 Issue: Volume: Page:
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Han Wei¹,Tang Ming-Yao¹,Chen Ye-Kun¹,Ma Mengtao²^ORCID,Shen Zhi-Liang¹^ORCID,Chu Xue-Qiang¹^ORCID

Affiliation:

1. Technical Institute of Fluorochemistry, Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China

2. Department of Chemistry and Materials Science, College of Science, Nanjing Forestry University, Nanjing 210037, China

Abstract

A defluorinative 1,2,3,4-tetrafunctionalization of perfluoroalkyl alkenes with readily available ureas via multi-bond interconversion at four carbon sites has been developed for the synthesis of perfluoroalkenyl 2-imidazolones.

Funder

National Natural Science Foundation of China

Nanjing Tech University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D4QO01173B

Reference43 articles.

1. 1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydroimidazol-2-one: A Selective High-Affinity Antagonist for the Human Dopamine D4 Receptor with Excellent Selectivity over Ion Channels

2. Enoximone in cardiac arrest caused by propranolol: two case reports

3. Caprolactams as potent CGRP receptor antagonists for the treatment of migraine

4. Discovery of the first antibacterial small molecule inhibitors of MurB

5. 2-Imidazolidinones as Chiral Auxiliaries in Asymmetric Synthesis

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