The synthesis, characterisation and cytotoxicity of bisintercalating (2,2′:6′,2′′-terpyridine)platinum(ii) complexes
Author:
Affiliation:
1. Nanoscale Organisation and Dynamics Group
2. School of Science and Health
3. University of Western Sydney
4. NSW
5. Australia
Abstract
Dinuclear (2,2′:6′,2′′-terpyridine)platinum(ii) complexes were synthesised by tethering either thiol or pyridine based linkers. The cytotoxicity of the complexes was determined against human ovarian carcinoma cells (A2780) and its cisplatin-resistant sub-line A2780cis, as well as L1210 murine leukemia cells.
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/DT/C4DT02773F
Reference37 articles.
1. Synthetic Methods for the Preparation of Platinum Anticancer Complexes
2. Drugs which affect the Structure and Function of DNA
3. Cellular interactions of platinum drugs
4. DNA-Damaging Agents in Cancer Chemotherapy: Serendipity and Chemical Biology
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