A cinchona alkaloid catalyzed enantioselective sulfa-Michael/aldol cascade reaction of isoindigos: construction of chiral bispirooxindole tetrahydrothiophenes with vicinal quaternary spirocenters-Reference-Cited by-同舟云学术

A cinchona alkaloid catalyzed enantioselective sulfa-Michael/aldol cascade reaction of isoindigos: construction of chiral bispirooxindole tetrahydrothiophenes with vicinal quaternary spirocenters

Published:2015 Issue:22 Volume:13 Page:6371-6379
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Gui Yong-Yuan¹²³⁴⁵,Yang Jian¹²³⁴⁵,Qi Liang-Wen¹²³⁴⁵,Wang Xiao¹²³⁴⁵,Tian Fang¹²³⁴⁵,Li Xiao-Nian⁶⁷³⁸⁹,Peng Lin¹²³⁴⁵,Wang Li-Xin¹²³⁴⁵

Affiliation:

1. Key Laboratory of Asymmetric Synthesis & Chirotechnology of Sichuan Province

2. Chengdu Institute of Organic Chemistry

3. Chinese Academy of Sciences

4. Chengdu 610041

5. P.R. China

6. State Key Laboratory of Phytochemistry and Plant Resources in West China

7. Kunming Institute of Botany

8. Kunming 650201

9. China

Abstract

Enantioselective sulfa-Michael/aldol reaction of isoindigos has been successfully developed to afford bispirooxindole tetrahydrothiophenes with vicinal quaternary spirocenters.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00774G

Reference71 articles.

1. Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction

2. Total Synthesis of Spirotryprostatin A, Leading to the Discovery of Some Biologically Promising Analogues

3. The Asymmetric Total Synthesis of (+)- and (−)-Spirotryprostatin B

4. Enantiospecific Synthesis of (+)-Alstonisine via a Stereospecific Osmylation Process

5. Pyrrolidinyl-Spirooxindole Natural Products as Inspirations for the Development of Potential Therapeutic Agents

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