Cholesterol enhances influenza binding avidity by controlling nanoscale receptor clustering
Author:
Affiliation:
1. Department of Chemistry
2. Stanford University
3. Stanford CA 94305
4. USA
5. Department of Molecular Physiology and Biomedical Engineering
6. University of Virginia
7. Charlottesville
8. Science for Life Laboratory
Abstract
Single-virus binding measurements and simulations show how cholesterol-mediated clustering of receptors controls influenza membrane-binding avidity.
Funder
Knut och Alice Wallenbergs Stiftelse
Stanford Bio-X
National Institute of General Medical Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/SC/C7SC03236F
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4. Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets
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