Lanmodulin remains unfolded and fails to interact with lanthanide ions in Escherichia coli cells

Author:

Wu Qiong12,Liu Xiaoli1,Chai Zhaofei1,Cheng Kai1,Xu Guohua1,Jiang Ling1,Liu Maili1ORCID,Li Conggang12ORCID

Affiliation:

1. Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan National Laboratory for Optoelectronics, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, 430071, China

2. Graduate University of Chinese Academy of Sciences, Beijing, 100049, China

Abstract

We have directly observed that lanmodulin remains unfolded in the presence of lanthanide ions in E.coli cells using the 19F NMR technique.

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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