Ultrasensitive two-dimensional material-based MCF-7 cancer cell sensor driven by perturbation processes

Author:

Chan Sophia S. Y.1ORCID,Lee Denise1ORCID,Meivita Maria Prisca1ORCID,Li Lunna1ORCID,Tan Yaw Sing2ORCID,Bajalovic Natasa1ORCID,Loke Desmond K.13ORCID

Affiliation:

1. Department of Science, Mathematics and Technology, Singapore University of Technology and Design, Singapore 487372, Singapore

2. Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore 138671, Singapore

3. Office of Innovation, Changi General Hospital, Singapore, 529889, Singapore

Abstract

A direct current (DC) resistance sensor based on two-dimensional (2D) molybdenum disulfide (MoS2) was developed to enable cancer cell-specific detection via micro-changes in the cancer cell membrane.

Funder

Ministry of Education – Singapore

Agency for Science, Technology and Research

Singapore University of Technology and Design

Zhejiang University

International Design Centre

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Reference89 articles.

1. Detection of COVID-19: A review of the current literature and future perspectives

2. National Cancer Institute, Cancer Statistics – National Cancer Institute, https://www.cancer.gov/about-cancer/understanding/statistics , accessed 3 May 2021

3. A.Lim , 10 Important Cancer Statistics in Singapore (Updated 2021) , https://smartwealth.sg/cancer-statistics-singapore/ , accessed 28 June 2021

4. Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention

5. Cell membrane modulation as adjuvant in cancer therapy

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