Chemistries of bifunctional PROTAC degraders-Reference-Cited by-同舟云学术

Chemistries of bifunctional PROTAC degraders

Published:2022 Issue:16 Volume:51 Page:7066-7114
ISSN:0306-0012
Container-title:Chemical Society Reviews
language:en
Short-container-title:Chem. Soc. Rev.

Author:

Cao Chaoguo¹²^ORCID,He Ming¹,Wang Liguo¹^ORCID,He Yuna¹,Rao Yu¹^ORCID

Affiliation:

1. Ministry of Education (MOE) Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing 100084, P. R. China

2. Tsinghua-Peking Center for Life Sciences, Beijing 100084, P. R. China

Abstract

Proteolysis targeting chimeras (PROTACs) technology is a novel and promising therapeutic strategy using small molecules to induce ubiquitin-dependent degradation of proteins.

Funder

National Natural Science Foundation of China

National Major Science and Technology Projects of China

National Key Research and Development Program of China

Postdoctoral Research Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CS/D2CS00220E

Reference274 articles.