Ruthenium-catalysed C–H/C–N bond activation: facile access to isoindolinones

Author:

Hu Xiao-Qiang12345ORCID,Hou Ye-Xing12345,Liu Zi-Kui12345,Gao Yang6785ORCID

Affiliation:

1. Key Laboratory of Catalysis and Energy Materials Chemistry of Ministry of Education & Hubei Key Laboratory of Catalysis and Materials Science

2. School of Chemistry and Materials Science

3. South-Central University for Nationalities

4. Wuhan 430074

5. China

6. School of Chemical Engineering and Light Industry

7. Guangdong University of Technology

8. Guangzhou

Abstract

A facile ruthenium-catalysed C–H/C–N bond activation and the subsequent annulation of readily available benzoic acids with in situ generated formaldimines are developed for the efficient synthesis of a wide range of biologically important isoindolinones.

Funder

South-Central University of Nationalities

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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