Ultra-rapid modulation of neurite outgrowth in a gigahertz acoustic streaming system

Author:

He Shan1234,Wang Zefang534,Pang Wei1234,Liu Chang1234,Zhang Miaosen1234,Yang Yang1234,Duan Xuexin1234ORCID,Wang Yanyan1234ORCID

Affiliation:

1. State Key Laboratory of Precision Measuring Technology & Instruments

2. School of Precision Instruments and Optoelectronics Engineering

3. Tianjin University

4. People's Republic of China

5. School of Life Sciences

Abstract

A gigahertz acoustic streaming effect stimulates PC12 cell structure change within 10 min, and produces a higher ratio of neurite-bearing cells compared to NGF stimulation. This method can be of single-cell modulation due to microminiaturization.

Funder

National Natural Science Foundation of China

Tianjin University

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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