A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures-Reference-Cited by-同舟云学术

A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures

Published:2016 Issue:10 Volume:14 Page:2938-2943
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Esposito V.¹²³⁴,Pepe A.⁵⁶⁷⁴,Filosa R.⁸⁹¹⁰⁴,Mayol L.¹²³⁴,Virgilio A.¹²³⁴,Galeone A.¹²³⁴

Affiliation:

1. Department of Pharmacy

2. University of Naples “Federico II”

3. 80131 Naples

4. Italy

5. Department of Science

6. University of Basilicata

7. Potenza

8. Department of Experimental Medicine

9. Second University of Naples

10. 80138 Napoli

Abstract

5-Amino-2′-deoxyuridine forms an eight hydrogen-bonded tetrad stabilizing a parallel G-quadruplex structure more efficiently than tetrads formed by 5-bromo-2′-deoxyuridine and thymidine.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C5OB02358K

Reference31 articles.

1. G-quadruplexes and their regulatory roles in biology

2. Potential uses of G-quadruplex-forming aptamers

3. “Nano-oddities”: Unusual Nucleic Acid Assemblies for DNA-Based Nanostructures and Nanodevices

4. Structural Investigations on the Anti-HIV G-Quadruplex-Forming Oligonucleotide TGGGAG and Its Analogues: Evidence for the Presence of an A-Tetrad

5. Tetramolecular DNA Quadruplexes in Solution: Insights into Structural Diversity and Cation Movement

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